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Grant Opportunities from the Department of Defense

Department of Defense Peer Reviewed Orthopaedic Research Program
Funding Opportunities for Fiscal Year 2011
Preproposal Due Date September 7, 2011

The PRORP was established in fiscal year 2009 (FY09) to support research focused on optimizing recovery and restoration of function for military personnel with orthopaedic injuries sustained in combat or combat-related duties. Appropriations for the PRORP in FY09 and FY10 totaled $134.5 million (M). The FY11 appropriation is $24M.

The FY11 PRORP challenges the scientific community to address the most significant gaps in care for the leading burden of injury and loss of fitness for military duty by funding innovative, high-impact, clinically relevant research to advance optimal treatment and rehabilitation from musculoskeletal injuries sustained during combat or combat-related activities. Applications involving multidisciplinary collaborations among academia, industry, the military services, the Department of Veterans Affairs (VA), and other Federal Government agencies are highly encouraged.

All applications for PRORP funding must specifically address at least one of the topic areas as directed by Congress, and must be directly relevant to the health care needs of the military service members, veterans, and/or beneficiaries. If the proposed research is not relevant to FY11 PRORP topic areas, the Government reserves the right to administratively withdraw the application. The Government also reserves the right to reassign the application's topic area if submitted under an inappropriate topic area.

Please use the following link to retrieve the eligibility requirements, deadlines and additional details for each award mechanism.

http://cdmrp.army.mil/funding/prorp.shtml

Technology Development Award - Maximum funding $2 Million direct costs
* Preproposal is required; application submission is by invitation only
* Support studies for the design, development and demonstration of a modular, interoperable, three-degrees-of-freedom, externally-powered prosthetic wrist with a one-degree-of-freedom terminal device and accompanying control strategies
* Preliminary and/or published data are required
* Does not support definitive clinical trials, but limited clinical testing is permissible
* All applications must have a direct relevance to orthopaedic injuries sustained during combat or combat-related activities

Clinical Trial Award - Maximum funding $2.5M for direct costs
* Preproposal is required; application is by invitation only
* Supports the rapid implementation of clinical trials that will have a significant impact on military combat-related orthopaedic injuries in the areas of prevention and treatment of post-traumatic osteoarthritis and improved outcomes for severe limb injuries
* IND or IDE applications should be submitted before full application submission
* Preliminary data are required
* Military/Veteran study population highly encouraged
* Optional Nested Career Development Award: Additional funds may be requested to support the mentored career development of an active duty military research-scientist or physician-scientist at an early career stage

Translational Research Partnership Award - Maximum funding $750K for direct costs
* Preproposal is required; application submission is by invitation only
* Supports the development of multidisciplinary translational research partnerships between clinicians and laboratory scientists to accelerate the movement of promising research hypotheses into clinical applications
* Minimum of 2 PIs required; maximum of 3 PIs allowed
* At least one partner must be a laboratory scientist and at least one partner must be a clinician
* At least one partner must have significant experience in orthopaedic research or orthopaedic medicine
* Must address FY11 PRORP Focus Areas of prevention and treatment of post-traumatic osteoarthritis or improved outcomes of severe limb injuries
* Preliminary and/or published data are required
* Does not support definitive clinical trials, but limited clinical testing is permissible
* All application must have a direct relevance to orthopaedic injuries sustained during combat or combat-related activities

All applications must conform to the program announcements and application instructions that are available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all USAMRMC funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

A pre-application will be required and must be submitted through the CDMRP eReceipt website (http://cdmrp.org) prior to the pre-application deadline of September 7, 2011. Applications must be submitted through the federal government's single-entry portal, Grants.gov. Requests for email notification of the program announcements release may be sent to . For more information about the PRORP or other CDMRP-administered programs, please visit the CDMRP website ( http://cdmrp.army.mil).

Points of Contact:
CDMRP Public Affairs
301-619-9783

For additional information, contact Brianna Griesbach at brgriesbach@wisc.edu

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